This paper uses total internal reflection microscopy (TIRF) to visualize single molecules of proteins that are important in decoding, copying, and rearranging DNA.
Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA, Bell JC et. al., Nature, 8 Nov 2012, 274-278
Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA, Bell JC et. al., Nature, 8 Nov 2012, 274-278